FOCUS AND GOALS This symposium seeks to highlight recent technological advances that have changed, or will change, the way we study cancer and the ways we treat patients. Topics will include new ways to create chemical diversity, to choose drug targets, to pharmacologically address “undruggable” drug targets, to interrogate cancer with heretofore unimaginable spatial and temporal resolution (including at the single cell level), and to reengineer the immune system for therapeutic benefit.